Agreement gives Iksuda access to Femtogenix’s therapeutic payloads to advance lead ADC for difficult-to-treat solid tumours
Newcastle, UK, 5th March 2019: Iksuda Therapeutics (Iksuda), the next-generation Antibody Drug Conjugate (ADC) company, today announced it has signed a licensing agreement with Femtogenix Limited (FGX), the next-generation ADC payload company. As part of this agreement, Iksuda will use FGX’s sequence-selective DNA-interactive payload molecules to progress its lead ADC towards the clinic, with the aim of targeting difficult-to-treat solid tumours.
By harnessing FGX’s highly potent and broad-acting DNA mono-alkylating payloads in combination with its own PermaLink® conjugation platform, Iksuda aims to significantly improve the therapeutic index of its ADCs and further advance the current standard of care for solid tumour types, which can be resistant to treatment. The agreement marks another key step in the build-out of Iksuda’s ADC technology-suite and drug pipeline, from which it aims to progress multiple candidates towards first clinical studies in 2020.
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